Precision medicines have revolutionised the treatment of some cancers and rare genetic diseases, yet progress in chronic diseases such as heart failure has lagged.
The challenge is that chronic diseases, like heart failure, are biologically complex and driven by multiple mechanisms. They are heterogenous; from how they present over time with an array of different symptoms and comorbidities, to the way they are diagnosed over the course of disease.
Heart failure affects 64 million people worldwide and has several underlying causes. Current heart failure treatments follow a ‘one-size-fits-all’ approach. Due to the wide range of mechanisms by which heart failure can occur, however, this is not always the best approach.
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